Effect of early treatment with hydroxychloroquine or lopinavir and ritonavir on risk of hospitalization among patients with COVID-19: the TOGETHER randomized clinical trial
Citations
165
41.3 per year
Published
2021

Effect of early treatment with hydroxychloroquine or lopinavir and ritonavir on risk of hospitalization among patients with COVID-19: the TOGETHER randomized clinical trial

JAMA Network Open2021
Authors

G Reis, EASM Silva, DCM Silva, L Thabane, AC Ferreira, VEG Souza-Campos, AM Nogueira, APM Almeida, EDS Callegari, ADF Figueiredo-Neto, L Sprague, H Hendrickson, JI Forrest, P McKenzie, AA Gordon, K Thorlund, EJ Mills

COVID-19
Hydroxychloroquine

Abstract

Importance: Data on the efficacy of hydroxychloroquine or lopinavir-ritonavir for the treatment of high-risk outpatients with COVID-19 in developing countries are needed. Objective: To determine whether hydroxychloroquine or lopinavir-ritonavir reduces hospitalization among high-risk patients with early symptomatic COVID-19 in an outpatient setting.

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