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Resilient Clinical Trial Infrastructure in Response to the COVID-19 Pandemic: Lessons Learned from the TOGETHER Randomized Platform Clinical Trial
JI Forrest, A Rawat, F Duailibe, CM Guo, S Sprague, P McKay, G Reis, EJ Mills
Productive platform trials evaluating COVID-19 treatments often succeed because of intentional investment in resilient trial infrastructure. We characterise the TOGETHER Trial using a health-system resiliency framework so clinical trialists can build infrastructures that respond rapidly to global health threats.